How do you do? is not at all the same as How are you? People say How do you do? only when they are introduced to somebody that they don’t know. The reply is exactly the same: How do you do?
Ms. Smith: I don’t think you know each other. James Baldwin, this is Linda Black.
Ms. Smith: How do you do?
Linda Black: How do you do?
Translation:
Como vai você?
Como vai você?
Eliane Rabello 